Could E. Coli Bacteria be Both a Cancer
CAUSE and a Cancer CURE?
July 21st, 2013 by Holly Cornish
When you hear the words E. coli, the first thing you probably think of is food poisoning. And you wouldn’t be wrong—given that some strains of the bacteria have been linked to food recalls and serious illness.
Well, it might surprise you to learn there are harmless strains of the Escherichia coli bacteria that are a normal part of your intestinal flora — the “good” bacteria in your colon.
In fact, the good strains of E. coli can help you by producing vitamin K, a valuable nutrient that’s only recently started to get the attention it deserves (I take it as a supplement every day). E. coli can also keep harmful bacteria from setting up camp in your intestines.
So if E. coli can be so friendly—why are we talking about its connection to cancer? Glad you asked. . .keep reading. . .
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New research suggests that the normally harmless E. coli may change its nature if your gut is inflamed.
It seems that patients with inflammatory bowel syndrome (IBS) develop colorectal cancer at significantly higher rates than people who don’t have this digestive problem.
And one study from scientists at the University of North Carolina at Chapel Hill links this phenomenon with the presence of a strain of E. coli.
Christian Jobin, PhD, associate professor in the Division of Gastroenterology and Hepatology, led a team that raised mice with a gene mutation that makes them susceptible to inflammatory bowel disease.
After rearing the mice in germ-free cages, the scientists moved them to cages where bacteria-filled mice formerly lived.
According to results published in the journal Science, five months later, all of the mutant mice had developed bowel disease.
What’s more, the researchers found that 60 to 80 percent of the animals had developed colon cancer!
One common thread in the mutant mice was that they’d all developed a gut environment containing a much higher than normal proportion of E. coli.
And one E. coli strain that stood out was NC101, which was linked to aggressive forms of bowel disease in mice. This E. coli bacterium also produces the DNA-damaging protein colibactin.
In addition to these harmful bacteria, the researchers also found strains of E. coli in the gut that did not make colibactin.
These other bacteria were associated with bowel disease—but did not contribute to tumor formation.
How does this relate to colon cancer in humans?
Humans also can harbor the bacteria that produce colibactin. The North Carolina investigators found these bacteria at the following levels:
- In 20 percent of 24 healthy people
- In 40 percent of 35 people with inflammatory bowel disease
- In two-thirds of 21 people with colorectal cancer.
These are small samples, but if the rates hold up for the whole population, the findings indicate that people with IBS and colorectal cancer are infected with this damaging strain of E. coli at much higher rates.
The findings also indicate that many healthy people harbor this bug with no apparent problems. I’m willing to venture they can do this because they have strong immune systems plus plenty of “good” gut bacteria to keep the “bad” bacteria in check.
As to how the colibactin-producing bacteria lead to cancer—Jobin’s team isn’t completely sure.
One thought is that gut inflammation causes colibactin-producing strains to multiply.
At the same time, these proteins can cause cells lining the stomach to weaken—leaving them wide open to DNA damage.
Given enough time, cells subjected to these conditions can turn cancerous.
In essence, the study results suggest a direct link between changes in the gut microbiome (the total ecosystem of gut bacteria) and the development of inflammation and cancer.
Jobin said doctors could possibly construct a personalized plan for cancer prevention for each patient. This would involve using DNA sequencing to find microbes in a patient’s guts that could produce cancer-causing genes.
The doctors could then use antibiotics to eliminate these microbes or encourage the use of probiotics to destroy cancer promoting bacteria. Readers of this newsletter know I’m opposed to the use of antibiotics in all but the most dire circumstances.
The use of probiotics plus healthy eating habits (more fresh fruits and vegetables, few refined carbs) should create a healthy balance of gut bacteria in most people.
It’s important to understand that ALL of us have disease-causing microbes in our bodies, and we handle them just fine if we eat right and support our immune system.
Scientists across the pond have found a
different way to use E. coli
Remember, there are various strains of the E. coli bacteria. British researchers are working on a genetically altered strain of the virus as a possible treatment.
Their idea is to tinker with an E.coli bacterium to make it target and destroy cancer tumors.
Scientists at the Queen Elizabeth Hospital in Birmingham have managed to alter one strain of the virus to make it harmless to healthy human cells—while serving as an assassin to cancer cells.
A Daily Mail article describes how doctors used a common cold virus to deliver the E. coli bacteria to the cancer cells.
Simply put, the scientists have managed to arrest the poisons in E. coli until they reach the inside of cancer cells.
According to Dr. Nick James, the oncologist who coordinated the therapy trials, the researchers are targeting men who have been treated for prostate cancer, but experienced a recurrence of the disease.
Additional trials are underway to determine how this therapy could be helpful to patients with cancers of the head and neck, kidneys and liver.
So depending on the strain, E.coli may be either a cancer cause or a cancer cure. More research is needed on both angles before we know for sure. But you can be sure that eating plenty of whole grains, fruits and vegetables is one of the best ways to sweep gunk out of your colon.
Not only will it help you maintain a ‘smooth move’ in your bowels—but it could also help protect you from disease-producing germs and bacteria.
Meanwhile, I don’t want you to miss a very exciting new herbal cancer treatment that we unveiled in the last issue. The article reappears below if you didn’t see it last Wednesday.
Destroy Cancer Naturally in 40 Days
Ancient Chinese medicine is bringing renewed hope to cancer sufferers, all thanks to an herb called thunder god vine. For starters, this herb may make it possible to purge tumors from the body without resorting to chemotherapy or other intense interventions.
On top of that, early evidence shows thunder god vine could be particularly effective in hindering the growth of pancreatic, colorectal, and ovarian cancers, among others.
The One Word every cancer patient must know
Your doctor’s reading the results, you know it’s the worst news, and you snap out of it just in time to hear him say…
“I’m going to recommend an aggressive chemotherapy regimen.”
That’s when you say one word that sucks the air out of the entire doctor’s office.
It’s a new cancer therapy that doctors are whispering about behind closed doors…and doctors will be stunned you know about it.
$4 billion has already been spent researching it–making it one of the largest research initiatives in medical history.
And the results are powerful–Tumor shrinkage in 86% of lung cancer patients.
Once “incurable” brain tumors put on hold. And these revelations are already rushing 374 clinical trials into hospitals.
But you can’t call this new hope therapy “aggressive” like chemo, because there is no poison, there are no toxins.
In fact, this therapy could have you alive and thriving.
Find out the one word that will have your doctor asking, “how did you hear about this?”
How this natural remedy quickly slays cancer
The thunder god vine (Tripterygium wilfordii) is native to Japan, Korea, and China. For more than 400 years, those cultures have celebrated the healing properties of the plant, which include anti-inflammatory and immunosuppressive benefits.
The vine itself is a handsome perennial plant with small, white flowers. To get to the healing compounds, extracts are prepared from the skinned root of the thunder god vine. The leaves, flowers, and skin of the root are intensely poisonous and can cause death if eaten.
Known as “lei gong teng” in Mandarin, this plant’s skinned root has an uncanny ability to stop cancer in its tracks after as little as forty days of use. The speed and efficiency with which it appears to destroy tumors has stunned Western researchers.
The healing secret of thunder god vine lies in triptolide, an active compound with anti-cancer properties. Heavy doses of this compound are responsible for the vine’s therapeutic success. Triptolide appears to work by halting the production of RNA in cancerous cells, meaning the cancer cannot spread.
Researchers were shocked
by its cancer-killing power
At the University of Minnesota Masonic Cancer Center, researchers were shocked to find how effectively thunder god vine reduced the incidence of tumors in mice. Even after other treatments were stopped, thunder god vine appeared to fully eliminate the tumors.
Similar results were found at the John Hopkins School of Medicine, where extracts of thunder god vine were used to eliminate tumors. A professor involved in the research reported that even small extracts of the plant appeared to be effective in halting growth of all 60 of the cancer cell lines tested, and that in some cases the cell lines completely died off.
Because early studies with mice appear so promising, human clinical trials are expected to begin in the near future. Clinical trials in pancreatic cancer, known for being a virtual death sentence, will likely begin first.
The only known downside is that side effects can be severe. They include a loss of bone density, infertility problems, hair loss, menstrual changes, and headache. Gastrointestinal issues like diarrhea, indigestion, and nausea have also been reported. Some of those side effects sound serious, and I would like to know more.
For this reason, the treatment should be used under the guidance of a qualified practitioner, and unfortunately I can give you no guidance on finding one. I hope that some of the cancer doctors who read this publication will see this article and consider incorporating thunder god vine into their protocols. For now, a qualified practitioner of traditional Chinese medicine would be the most likely source of knowledge and clinical experience with actual patients.
If you’re in the U.S., it can be a challenge to get consistent, high-quality thunder god vine products. You may be able to get them directly from China, but be warned there’s no process for verifying their safety or efficacy.
Harness the power of this herb
while you can still get it cheap
Along with being such a potent cancer-killer, early evidence shows autoimmune disorders like rheumatoid arthritis, lupus, and multiple sclerosis also respond well to treatment with thunder god vine. It’s a potential wonder drug.
All this is terrific news, as is the fact that thunder god vine treatment is quite inexpensive. But be warned, with big dollars being poured into research on this herb, somebody down the line will undoubtedly come up with a triptolide drug that requires FDA approval and can be protected by patent. Needless to say, that means this low-cost, extremely effective treatment will be turned into an expensive merger between greed and healthcare.
The unpatented herb will still be available (I hope), but patients will be under pressure to use the pharmaceutical version.
In fact, the researchers from the University of Minnesota have already isolated a highly water-soluble form of triptolide and dubbed it minnelide, a combo-word of Minnesota and triptolide. They are in talks with the Food and Drug Administration and are currently preparing to launch a Phase I trial.
Meanwhile, let’s hope research on the natural form continues and an increasing number of doctors and patients begin to try it, thereby adding to our knowledge of this exciting discovery (and its side effects).
Lee Euler, Publisher