Newsletter #138
Lee Euler, Editor
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About Cancer Defeated!

Eight Types of Vitamin E —
And the Most Popular One is the WRONG One!

We've known for a while that vitamin E helps prevent cancer. But as it turns out, some forms of the vitamin are more powerful than others. And sometimes certain forms of this vitamin may actually increase your chance of developing cancer. Details follow. . .

Continued below. . .


The secret to curing cancer:
You've been throwing it in the trash!

In 1921, a British doctor discovered that a remote tribal people was almost totally cancer-free. But when members of this tribe move away from their native land and change their diet, they get cancer just like anyone else.

It's all thanks to a food most of us throw away as waste!

Click here now and watch a video presentation about this cancer breakthrough. One cancer expert calls this overlooked food "the key to curing AND preventing cancer" — and you can benefit NOW — without going to a doctor or buying expensive supplements. This little throwaway food tastes great. Bill Clinton (of all people) eats it regularly, and so can you. Click here now to watch the video!


Even though scientists have known about vitamin E since 1922, they've only started to figure out what it can really do in the last several years.

For starters, there are actually eight types of vitamin E. Four are "tocopherols," and four are "tocotrienols." Each group has an alpha, beta, gamma, and delta subtype. The main difference between tocopherols and tocotrienols is a slight variation in chemical structure.

When you buy vitamin E supplements in the store, chances are you're buying alpha-tocopherol. The ingredient list might say "alpha-tocopherol and mixed tocopherols," but the reality is that it's mostly alpha-tocopherol. Few vitamin E supplements include any form of tocotrienols.

Yet by some estimates, tocotrienols are 50 times more powerful than tocopherols. This makes them much more effective in disease prevention. Of course, they're also a lot more expensive. But for those who can afford it, the benefits are extreme.

Tocotrienols and their incredible healing properties

Overall, vitamin E has a good reputation in the natural health world because it's known to protect DNA from free radical damage — one of the causes of cancer. Other benefits are that it enhances the immune system, protects cell membranes, and shelters active enzyme sites from damage. It may even block the formation of nitrosamines (carcinogens that form in the stomach from nitrites).

Tocotrienols take that good reputation one step beyond. According to current research, this form of vitamin E effectively reduces cholesterol, protects against brain cell damage, and prevents cancer.

Tocotrienols don't occur in nature as often as tocopherols, but they are natural compounds. They can be found in varying concentrations in vegetable oils, wheat germ, saw palmetto, barley, and certain nuts and grains.

Commercial sources of tocotrienol are rice, palm, and annatto. (Annatto is a natural yellow-orange food coloring. It comes from the fruit of the achiote tree, found in tropical South America.)

What's interesting is that tocopherols — the form of vitamin E widely available in our supplement industry — don't appear to have the same biological characteristics as their tocotrienol siblings.

In chemical terms, tocotrienols have an unsaturated side-chain that allows them to quickly penetrate tissues coated with saturated fatty layers. This boils down to a more functional molecular "tail." It's not as long or as stiff as the chemical tail found on tocopherols, so it's easier for the compound to move around cells and neutralize free radicals — something tocotrienols do far more efficiently than tocopherols.

Tocotrienols are also better at reversing oxidative stress to skin that's been exposed to UV rays. Overall, they appear to be much more potent than tocopherols when it comes to prompting an anti-oxidation and anti-cancer effect.

What's strange is that this isn't really new information. Scientists suggested back in 2000 that tocotrienols make better antioxidants than tocopherols, particularly when it comes to cancer prevention. So here we've known for over a decade that tocotrienols are more powerful and more effective, yet current formulations of vitamin E supplements still consist mostly of alpha-tocopherol.

Worse, alpha-tocopherol seems to interfere with tocotrienol benefits by decreasing absorption ability. A recent Japanese study even showed that tocopherols, and alpha-tocopherol in particular, interferes with the ability of delta-tocotrienol to induce apoptosis (natural cell death) in cancer cells.1 It does this by blocking the absorption of delta-tocotrienol.

Little-known anti-cancer research with promising possibilities

In terms of cancer prevention and treatment, tocotrienols seem to be able to neutralize something called vascular endothelial growth factor (VEGF). This is important when you're battling cancer, since VEGF prompts the development of new blood vessels built to feed growing tumors.

This process whereby cancer forms its own network of blood vessels is called angiogenesis. If tocotrienols indeed slow down or stop BOTH angiogenesis AND apoptosis, it's a very big deal.

At the very least, we've seen this promising research come out about the specific benefits of tocotrienols:

  • Pancreatic cancer: Tocotrienols appear to be the more effective antioxidant over tocopherols thanks to their unsaturated side chain.

    That chain allows the compound to penetrate better into saturated, fatty layers of the liver and brain, which gives it an advantage in terms of halting the formation of tumors, DNA damage, and cell damage.

    A 1993 study on rats with liver cancer proved this.2 Less liver cell damage was detected in the group that received palm tocotrienols.

  • Breast cancer: In vitro studies conducted in the 1990s showed tocotrienols helped inhibit the growth of human breast cancer cells. Tocotrienols appeared to work synergistically with tamoxifen, (a common breast cancer medicine) to kill cancer cells.3

    Delta-tocotrienols appeared be the most effective in inducing apoptosis in cancer cells, and gamma-tocotrienols supposedly inhibit ld1, a key cancer-promoting protein.

  • Prostate cancer: Different studies show delta- and gamma-tocotrienols suppress prostate cancer cell proliferation. In contrast, another study showed that alpha-tocopherol enhanced cancer cell growth.4
  • Skin cancer: In a study at the University of Hong Kong, skin cancer cell numbers decreased when treated with gamma-tocotrienol and chemotherapy drugs.5 Other studies have shown tocotrienols suppress the growth of melanoma.6

These studies seem promising because they're focused specifically on tocotrienols. But as a whole the research is confusing. For example, some studies show lower prostate and breast cancer rates are associated with a higher intake of vitamin E. Yet, postmenopausal breast cancer incidence appears unaffected by vitamin E intake.

Part of the problem is that the scientific community only recently started to pay attention to tocotrienols. Most research up until a few years ago focused on alpha-tocopherol. Studies on tocotrienols made up less than 1% of total research on vitamin E.

That's starting to change. Now researchers have ramped up their efforts to understand tocotrienols. In the past few years, almost 30% of the peer-reviewed studies on vitamin E have been specific to tocotrienols.

Based on those few studies, tocotrienols so far have been shown to be safe. They appear to have no adverse effects when taken for a period as long as four years (the length of the longest study to date).

Right now, a study going on at the Moffitt Cancer Center and Research Institute in Tampa, Florida, is recruiting participants for a study on tocotrienols. Researchers are hoping to determine the safest dose of delta-tocotrienol. They also want to establish how often it should be taken, along with how well it helps patients with pancreatic tumors. The study won't be completed till 2013.

How to get hold of this natural, cancer-altering treatment

You can buy tocotrienol supplements without alpha-tocopherol, but they're expensive. You want to look for supplements that are mostly made up of tocotrienols, with 15% or less of alpha-tocopherol.

You also want to look for supplements derived from natural sources — at least for now. It's known that synthetic mixtures of tocopherols are not the biological equivalent to naturally occurring compounds, though they're widely used in academic research and in commercial products. In fact, this is one of the problems with a lot of vitamin studies to date — they use synthetic tocopherols.

If you can afford tocotrienol supplements, you probably won't have much trouble avoiding synthetic products because they're not yet widely available. In theory, they should be relatively cheap to produce. They'd also likely provide many of the same clinical benefits natural tocotrienol appears to have.

Meanwhile, the research on widely-available alpha-tocopherol is confusing and contradictory. I wouldn't take more than 400 i.u. a day, given the strange studies that suggest it may actually promote cancer under some circumstances.

I'm sure this statement will bring me a few angry emails from readers, but it's a fact that the status of alpha-tocopherol is not at all clear right now. The research shows a confusing array of benefits and possible risks, with little to gain from taking large doses.

If you're looking for the most powerful anti-cancer properties from vitamin E, go for the tocotrienols. You'll probably have to pay a hefty price … but it might be worth it.

As our last issue mentioned, nuts (especially walnuts) are a rich source of vitamin E and are probably a better bet than alpha-tocopherol pills. In fact, just eating walnuts can knock back the growth of cancer cells as much as 40%! If you missed this article, you can scroll down and catch it now. . .


The Crunchy, Go-Anywhere
Cancer-Fighting Snack

Simply eating a lot of walnuts may inhibit prostate cancer growth or stop it outright.

That was the finding of Paul Davis, UC Davis Cancer Center researcher. He proved the impact of walnuts by studying mice genetically programmed to develop prostate cancer.1 The results were startling. Details follow this word about one of the fine books we publish. . .

Continued below. . .


Ten-year breast cancer survivor was told:
"You'll be dead in a year" (Pssst!! That was 10 years ago!)

Doctors didn't give Wiltrude much hope when they diagnosed her with cancer in the year 2000. Wiltrude, a German psychologist, never thought cancer would happen to her. But it did. And it came as a big shock.

One doctor told her, "You'll be dead in a year." Late stage breast cancer is virtually incurable using conventional treatments. Even M.D.s admit it. They talk about "buying you more time." (Don't count on it. The evidence shows you're better off doing nothing than chemo.)

When Wiltrude told her doctor she was going to try alternative treatments, he said, "You are committing suicide with what you're doing." But she was determined to find a way to beat her cancer.

Thanks to the wonders of the Internet, this European woman came across a book by my good friend Bill Henderson, one of the smartest and wisest people I know when it comes to cancer treatment.

She tried Bill's top, number one recommendation — a gentle treatment you can do at home for just $5.15 a day. What's more, the cost goes down to $3.50 after six weeks because you just need a maintenance dose. And it even tastes good.

Not only has Wiltrude passed the five-year cancer survival mark, she's survived for ten years. We just interviewed her recently for this publication. The radiologist who tests her every year told her, "You're the only one with this kind of result."

You can find out about Bill’s proven cancer treatment plan in a free video presentation — click here to watch it now.

When I ask him about some of the treatments that top alternative doctors use, Bill sort of shrugs and says, "They're fine, but why bother? My treatment works, you can do it yourself, and it costs practically nothing."

He's coached thousands of cancer patients with all different types and stages of cancer. Most of the people who follow the detailed, specific plan in this Special Report get over their cancer and live for years.

"Almost any kind of cancer is reversible," says Bill. "I never give up on anyone."

Click here and watch the free video presentation about Bill’s amazing cancer protocol.


In Davis's experiment, the mice eating the human equivalent of 2.4 ounces of whole walnuts daily for 18 weeks had significantly smaller and slower growing prostate tumors than did the control group eating equivalent fats from other sources.

The whole walnut diet slashed prostate cancer growth by 30-40%.2

The study also established that walnuts affected multiple genes which control tumor growth. And walnuts aren't the only nut with healthy benefit. . .

Nuts may be that rare thing — something that's
fun to eat AND good for you

Portable, long shelf life, nutritious, no preparation needed…

One of the most convenient and nutritious snack foods available… Yet nuts get a bad rap for being "too high-fat".

But placing all the focus on their high fat level is missing the big picture. Nuts can be an important part of a low-carb diet. And after many years of hearing the arguments fly back and forth, and doing some experimenting on myself, I've decided carbs are the main enemy, not fats.

It was the cancer connection that was the last straw for me. Refined carbohydrates have a clear role in promoting cancer — not to mention diabetes and heart disease. And nuts are a great way of getting off carbs.

Nuts are a rich storehouse of omega-3 fatty acids and flavonoid antioxidants (carotenes, quercetin, resveratrol, and lutein) — with the added benefit of fighting inflammation. Nuts reduce your risk of:

  • Various cancers
  • High blood pressure, coronary artery disease
  • Strokes
  • Arthritis
  • Alzheimer's, schizophrenia, and depression.

Nuts have mineral power too… manganese, potassium, calcium, iron, magnesium, zinc, and selenium.

Manganese helps you produce the enzyme superoxide dismutase, a powerful free radical scavenger. Potassium helps control heart rate and blood pressure. And your body needs copper and iron to produce red blood cells.

What's more, nuts are a good source of B-complex vitamins, critical for energy and well-being.

Lastly, they provide high levels of vitamin E — a powerful lipid-soluble free radical scavenger.

Despite the warnings about the "high fat" content of nuts, I couldn't find evidence showing that eating nuts causes weight gain. In fact, replacing pastas and breads with a handful of nuts may control insulin resistance and help you lose weight.

Nuts are rich in this known cancer-fighter

Selenium shows great promise as a cancer preventive. Many studies show it's an effective tool against breast, esophageal, stomach, prostate, liver and bladder cancers. And it's an especially strong free radical scavenger that works synergistically with vitamins C, E and beta-carotene.

A 1996 study by Dr. Larry Clark showed a staggering 42% cancer rate reduction in those who took 200 micrograms of selenium daily for seven years, versus the placebo group. And in the selenium group, death rates were half that of the placebo group. Best results were for prostate, colorectal, and lung cancers.

Jean Carper, in Miracle Cures, called Dr. Clark's findings an "unprecedented cancer intervention study" that "bumped up the respectability of using supplements against cancer several notches."

Many foods contain selenium… But the bioavailable amount is heavily dependent on how selenium-rich the soil is. Soils rich in volcanic ash or in sediment deposited by sea water boast a higher selenium content than do other types of soil.

In the long run, your cancer risk may be determined by selenium levels where you live (assuming you eat locally grown food and don't take a selenium supplement). One theory for why cancer rates are so high in Linxian, China, dubbed "the world capital of cancer", is that the soil is woefully deficient in selenium and zinc.

It's been suggested that one reason American men are five times more likely to die from prostate cancer than Japanese men is that in general, "the Asian diet contains four times the amount of selenium as the average American diet."

What does selenium do? It activates an enzyme called glutathione peroxidase, which scavenges free radicals. Test tube studies show this enzyme inhibits tumor growth and regulates the natural life span of cells — ensuring they die when they're supposed to, instead of turning "immortal".

What else does selenium do?

  • Converts hydrogen peroxide to water (preventing lipid peroxidation)
  • Acts as an immune stimulant
  • Produces antibodies
  • Maintains a healthy heart and liver

Dr. Andrew Weil suggests this simple way to bump up your selenium levels…

Eat Brazil nuts!

Just one shelled Brazil nut — grown in central Brazil's selenium rich soil — gives you 120 micrograms of this mineral, getting you more than half way to your daily target of 200 micrograms.3

A staple in the Brazilian diet, these nuts — though high in fat and calories — actually reduce LDL cholesterol (the bad stuff), raise HDL (good cholesterol), and prevent cardiovascular disease and stroke. They're high in vitamin E, the B-vitamins, and minerals. Remember, selenium is more powerful when combined with vitamin E.

Selenium is especially important for those with prostate cancer.4

Like many nuts, Brazil nuts can cause allergic reactions in sensitive people, such as itchy mouth, wheezing, tight throat, hives, and even severe anaphylactic reaction. If you experience any symptoms after eating nuts, this issue's health tip is not for you. Consider taking a selenium supplement instead.

Excessive selenium levels may create toxicity. But since most people are deficient, that's a small concern.

What other specific kinds of nuts offer big health benefits? Check these out. Maybe you'll find a new excuse to eat your favorites.

Double the antioxidants of other nuts

You might want to eat a handful of walnuts every day to get the benefit of their potent antioxidant effects.

They deliver a near perfect balance of vitamins, minerals, and fiber — and also boast healthful oleic acid and omega-3 fats which lower deadly artery-clogging LDL cholesterol. Making walnuts part of your daily diet can help ward off cardiovascular disease and cancer.

Dr. Joseph Vinson compared walnuts to nine other nut species high in antioxidants — and found walnut's antioxidants were 2 to 15 times more powerful than vitamin E, doing more for your health than peanuts, almonds, pecans or pistachios.

His analysis also found that eating walnuts in their raw and natural form provides higher nutrient levels, because heating and roasting degrade its antioxidants.

Walnut's other benefits?

  • Lower LDL and higher HDL5
  • Rich source of vitamin E — a powerful lipid soluble free radical scavenger6
  • Packed with B-complex, magnesium, zinc, calcium, iron, copper, selenium7
  • Contain melatonin, ellagic acid, vitamin E, carotenoids, and poly-phenolic compounds8
  • Fights cancer, inflammation, aging, heart attacks, stroke and neurological disease9

Walnuts may be particularly helpful for breast10 and prostate11 cancers. As mentioned at the beginning of this article, a diet rich in walnuts resulted in a 30 to 40 percent reduction in prostate cancer growth in mice.

And then there's…

The raw nut that's not really raw

Almonds have long been a symbol for wellness and health.

Like other nuts, they offer healthy levels of fats, vitamins, minerals, phyto-nutrients, vitamin E, B-complex vitamins, selenium, and other antioxidants. They're also gluten free and part of a Mediterranean diet.

As you might expect, they're protective against coronary disease, cancer, diabetes, Alzheimer's, and more.12

Almonds' high levels of folic acid are believed to help lower homocysteine levels, cutting your risk of arterial buildup. One study showed that just 3 ounces per day lowered cholesterol by 14%.13

Their high fiber improves digestive function, reduces constipation, and lowers colorectal cancer risk.

Almonds help control your blood sugar levels, too, making this snack beneficial for diabetics, the insulin resistant, and the overweight. Plus, munching on a few almonds after work may make you less inclined to overeat at dinnertime.

As with any food, once you heat it, you denature the proteins and make it less bioavailable. But unfortunately, the U.S. government has taken that risk to a whole new level.

Warning — U.S. 'raw' almonds are NOT raw!

In 2001 and 2004, there were small salmonella outbreaks associated with just two specific almond growers. The U.S. Department of Agriculture seized the excuse to mandate pasteurization of U.S. almonds. They make no exceptions for organic almonds, especially after organic almond growers opposed to pasteurization lost a lawsuit on this issue in 2009. All domestically grown almonds must be pasteurized, post 2007.

Not to worry, though… Richard Waycott, CEO of the Almond Growers of California reassures us that they no longer use heat or radiation to pasteurize.

Instead they use propylene oxide!

Per Wikipedia, propylene oxide was once used as a racing fuel, but that practice is now prohibited under the National Hot Rod Association rules for safety reasons. (Ironic, isn't it?) It was used in glow fuel for model aircraft and surface vehicles, typically as an additive in small percentages of around 2% to the typical methanol, nitromethane, and oil mix. And, it's also used in thermobaric weapons.

Warnings from the EPA's Hazard Summary sheet on propylene oxide:

  • Short-term exposure causes eye and respiratory tract irritation.
  • Skin contact, even diluted, causes irritation and necrosis in humans.
  • Depresses the central nervous system (CNS) in humans.
  • Causes tumors near the site of administration in rodents.
  • Classified as a probable human carcinogen (Class 2B) by the EPA.

But yet, it's 'safe' for fumigating your almonds?

I can't recommend organically grown almonds.

You might be able to get true organic almonds by taking advantage of a loophole or two. You'd need to buy from a retailer or mail order supplier who sells imported almonds, or who buys from a farmer in amounts less than 100 pounds. Of course, this suggests that salmonella was never really the issue — but that's another whole story.

The rest of the nuts

In the space I've got, I can't go into detail on every conceivable nut. But certainly pecans and cashews rank high in popularity and deserve a mention here.

They both possess many of the qualities of other nuts.

Cashews contain small amounts of Zeaxanthin, a flavonoid antioxidant that can be absorbed into your eyes, and may be protective against age related macular degeneration. Cashews also contain healthy levels of selenium.

Pecans contain ellagic acid, which inhibits the DNA binding of certain carcinogens, protecting you from cancer.14 And they're a rich source of vitamin E.

Lastly, there's the peanut, which isn't actually a nut at all, but a legume. Peanuts boast many of the same nutrients as true nuts, including antioxidants. They protect from cancer (particularly stomach cancer), heart disease, degenerative nerve diseases, Alzheimer's, and more.

However, besides being a common and sometimes serious allergen, peanuts are susceptible to fungal (read: mold) infection from aflatoxin — a very powerful and dangerous toxin known to cause cancer and liver cirrhosis. Roasting helps reduce its toxic load, but other nuts may give you more health benefits with less risk.

The bottom line on nuts…

Provided you don't have nut allergies, they provide many health-protective benefits not easily achievable by replacement with other foods. I eat raw nuts, not roasted and salted, and I buy organic whenever possible.

Interesting question: Are pesticides, herbicides and fertilizers actually used much in growing nuts? It doesn't seem to me that nuts would be subject to pests since they're protected by a shell. And they're grown on a tree, so why would a grower need herbicides? A lot of smart people read this newsletter, so maybe someone out there can answer this question. If my guess is right, it may not matter much if you eat nuts that aren't organic.

Nuts are a great option for wholesome gifts during the holidays and any time — much better than candy and cookies. And you do a great favor to diabetics and the insulin resistant to provide nuts at parties and family get-togethers.

Kindest regards,

Lee Euler,
Publisher


Footnotes 1st article:

1Shibata A, Nakagawa K, Sookwong P, Tsuduki T, Asai A, Miyazawa T (June 2010). "alpha-Tocopherol attenuates the cytotoxic effect of delta-tocotrienol in human colorectal adenocarcinoma cells". Biochem. Biophys. Res. Commun. 397 (2): 214-9.
2 Rahmat A., et al. "Long-term administration of tocotrienols and tumor-marker enzyme activities during hepatocarcinogenesis in rats." http://www.ncbi.nlm.nih.gov/pubmed/8102564
3 Guthrie, Najla, et al. "Inhibition of Proliferation of Estrogen Receptor-Negative MDA-MB-435 and -Positive MCF-7 Human Breast Cancer Cells by Palm Oil Tocotrienols and Tamoxifen, Alone and in Combination." http://jn.nutrition.org/content/127/3/544S.long
4 Campbell, Sharon. et al. "?-Tocotrienol induces growth arrest through a novel pathway with TGF?2 in prostate cancer." http://www.sciencedirect.com/science/article/pii/S0891584911000979
5 Piek Ngoh Chang, et al. "Evidence of ?-Tocotrienol as an Apoptosis-Inducing, Invasion-Suppressing, and Chemotherapy Drug-Sensitizing Agent in Human Melanoma Cells." http://www.tandfonline.com/doi/abs/10.1080/01635580802567166
6 McAnally, Jennifer, et al. "Tocotrienols Potentiate Lovastatin-Mediated Growth Suppression In Vitro and In Vivo." http://ebm.rsmjournals.com/content/232/4/523.long

References 1st article:

"Chemoprevention of Tocotrienols: The Mechanism of Antiproliferative Effects." Wada, S. http://content.karger.com/ProdukteDB/produkte.asp?doi=10.1159/000212752

Passwater, Richard A. "Health Benefits Beyond Vitamin E Activity." Vitamin Connection, brochure.

Stengler, Mark. "The Rise of Vitamin 'T.'" Bottom Line Natural Healing, Vol 6 No. 6, June 2010.

"The Tocotrienols Going (Way) Beyond Vitamin E." An Interview with Barrie Tan, Ph.D. by Parris M. Kidd, Ph.D. Totalhealth, Vol. 30. No. 5 pgs 18-19.

Tocopherol. http://en.wikipedia.org/wiki/Tocopherol

Tocotrienol. http://en.wikipedia.org/wiki/Tocotrienols

"Vitamin E ?-Tocotrienol Administered to Subjects With Resectable Pancreatic Exocrine Neoplasia." http://www.clinicaltrials.gov/show/NCT00985777

Footnotes 2nd article:

1http://articles.mercola.com/sites/articles/archive/2010/04/10/walnuts-slow-prostate-tumors.aspx
2http://articles.mercola.com/sites/articles/archive/2010/04/10/walnuts-slow-prostate-tumors.aspx
3http://www.naturalnews.com/016446.html
4http://www.cancure.org/cancer_fighting_foods.htm
5http://www.nutrition-and-you.com/walnuts.html
6 http://www.nutrition-and-you.com/walnuts.html
7http://www.nutrition-and-you.com/walnuts.html
8http://www.nutrition-and-you.com/walnuts.html
9http://www.nutrition-and-you.com/walnuts.html
10http://www.cancer-c.com/mens-health/ways-to-prevent-breast-cancer.html
11http://articles.mercola.com/sites/articles/archive/2010/04/10/walnuts-slow-prostate-tumors.aspx
12http://www.naturalnews.com/006109.html
13http://www.naturalnews.com/006109.html
14http://www.nutrition-and-you.com/pecans.html


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