Newsletter #214
Lee Euler, Editor
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About Cancer Defeated!

This Herbal Migraine Cure
May Help Treat Cancer, Too

If you’re one of the unfortunate billion or so folks who suffer from migraines, you may already be familiar with this bitter-tasting tonic.

It’s a popular alternative treatment for migraines that’s been known for centuries, but gained new popularity in the 1980s in the U.K. A member of the sunflower family, it was commonly used in European folk medicine as a remedy for headaches, arthritis, and fevers.

More than 70% of the 270 U.K. people surveyed in one study reported feeling much better after taking two to three fresh leaves daily. Several human studies suggest the herb may reduce the frequency of migraine episodes in people who suffer from this painful health problem. But read on, because it may help with cancer too.

Continued below. . .

You’ve been told to avoid it at all costs. But–
This “forbidden” food could be the biggest health breakthrough of our time

    Your whole life, you’ve been warned that this substance can wreak havoc on your health.

But the bad rap could be for nothing. Because research proves this shunned food:

  • “washes away” stubborn bladder infections (often in less than 48 hours)
  • decreases tooth decay by 80%–without having to drop any of your favorite foods
  • reduces blood clots without the dangerous side effects of aspirin
  • cuts sinus and ear infections by 93%–One pioneering Texas doctor reports these results that are so dramatic his patients forget to keep using it!

And you should see how it helps you drop weight!

How can one food–especially one we’re told to stay away from–do so much?

More importantly–what is it? And how can you get your hands on it?

The name feverfew even comes from a Latin word meaning “fever reducer” — just as its name suggests.

The active compound in this plant is called parthenolide, which drug makers are also investigating. Scientists think parthenolide blocks substances that constrict the blood vessels and lead to migraines.

However, not all studies show that feverfew has a positive impact on migraines.

It seems to depend on your timing. It’s most effective when taken just as you feel the headache coming on. Another important factor is the quality of the supplement. Feverfew supplements should be standardized to a minimum of 0.2% parthenolide.

Feverfew actually works in a similar manner to ibuprofen — inhibiting the chemicals that cause your head to spasm.

Good for what ails your joints, too

    Not only does feverfew help reduce head spasms, it may also help reduce inflammation throughout your body. This may be valuable for those who suffer from inflammatory illnesses such as arthritis and rheumatoid arthritis (RA). In fact, feverfew has been used for centuries as a remedy for arthritis.

The herb is believed to hinder the hormone-like substances called prostaglandins — substances which cause pain and inflammation.

Some studies have even shown that feverfew inhibits inflammation better than NSAID drugs (Non-Steroidal Anti-Inflammatory Drugs)… truly good news for RA sufferers.

Most people believe feverfew’s positive activity comes from the compound parthenolide. However, a parthenolide-free feverfew extract also showed free radical-scavenging properties and protection from UV-induced sun damage.1

There’s more. Some researchers believe feverfew’s flavonol content may also contribute to its anti-inflammatory properties.2

New evidence that feverfew
may be cancer-protective

    Cancer is often regarded as an inflammatory disease. Like heart disease, arthritis, Alzheimer’s and many other diseases of aging, inflammation is certainly one of the major symptoms — and chronic inflammation may be a cause as well.

Feverfew’s active compound, parthenolide, is now being tested by scientists as a potential treatment for a variety of cancers… both as an alternative and complementary treatment.

Researchers at Indiana University School of Medicine started studying feverfew because parthenolide is known to inhibit the DNA-binding protein that turns genes on and off. This transcription factor is called NF-Kappa B, and is connected to cancer.

Harikrishna Nakshatri, PhD., Associate Professor, explains it this way… “NF-Kappa B is generally not active in a normal, healthy body, except when there is an infection or inflammation. Then it activates to help fight the infection. We have found, however, that it is always active in cancer.”3

According to Hakshatri, this “cancer hyperactivity” may be one mechanism involved in cancer metastasis.

How does feverfew perform against specific types of cancer? Here’s what science is discovering about this.

  • Breast Cancer. Tamoxifen is the world’s most widely prescribed cancer drug. Though we here at Cancer Defeated prefer alternative cancer treatments, if you’re inclined toward conventional treatments and want complementary ways to enhance your recovery chances, you’ll be interested in this study, and how it might help prevent resistance to Tamoxifen.4Patients with hormone-driven cancers are often given Tamoxifen, developed to block hormones from binding to cellular protein receptors. But many patients either don’t respond to the treatment or develop resistance to it.

    NF-Kappa B proteins trigger inflammation which can also signal tumor development. Feverfew’s parthenolide effectively suppresses NF-Kappa B.

    A Clemson University study tested feverfew against both breast cancer and cervical cancer cells. In this study, feverfew stopped the growth of all these cancer cells… as reported in the Spring 2006 issue of the Journal of Medicinal Food.

  • Secondary Lung Cancer. Dr. Nakshatri, mentioned above, discovered that parthenolide reduced breast cancer metastasis to the lungs by 25 percent. But due to the number of mice involved in the study, this result is not considered statistically significant.However, when parthenolide was combined with docetaxel — a common chemotherapy drug — lung metastasis went down by 50 percent compared to untreated animals.

    Dr. Nakshatri also gave mice a phytochemical from chamomile, called apigenin. It also blocks NF-Kappa G — though in a different way than parthenolide. Nakshatri hoped that these two compounds used in conjunction with docetaxel would enhance the drug’s benefit in stopping metastasis to the lungs. But it proved too toxic.5

  • Secondary Bone Cancer. In further research, Dr. Nakshatri is examining whether parthenolide and the drug docetaxel can stop breast cancer from spreading to the bone. (Bones and lungs are the most frequent sites for breast cancer metastasis.) He’s trying to get rid of the drug’s toxicity by combining it with natural substances like feverfew and chamomile.In my opinion, it would be most interesting to test apigenin and parthenolide without any drug use. But for the moment it appears this isn’t planned.

NF-Kappa B is now believed to play a significant role in many types of cancer — including leukemia, lung and prostate cancer. So parthenolide’s role as an NF-Kappa B inhibitor shows promise for a number of cancers besides breast cancer.

Perhaps most exciting of all —
can we now eradicate leukemia?

    Scientists at the University of Rochester Medical Center have made an exciting discovery…

An herbal extract of feverfew is reported effective against one type of human leukemia. Monica Guzman, PhD, and Craig Jordan, PhD, even go so far as to say that feverfew extracts can kill malignant stem cells like no other single therapy they’ve ever tested.

The U.S. National Cancer Institute is even excited enough by their work to have moved it into their rapid access program — which fast-tracks experimental drugs from lab to human clinical trials.

Says Dr. Jordan, “We have proof that we can kill leukemia stem cells with this type of agent, and that is good news.”

What’s very promising is that this is the first agent known to destroy myeloid leukemia at the stem cell level. This is where malignancy is actually born. And scientists already know that unless it is attacked at the stem cell level, it can hardly ever be controlled, let alone cured.

Researchers in the late 1800s proposed the theory that cancer could be caused by stem cells undergoing malignant change. The work of John Beard (1858-1924) was at first greeted by interest, but later maligned and forgotten. His findings were only kept alive through the years by a few maverick biologists — among them, Dr. William D. Kelley, whom we’ve written about in our Special Report on enzyme therapy, The Missing Ingredient for Good Health.

The stem cell connection

    More recently, scientists discovered cancer stem cells in blood, brain, and breast cancers.

Two scientists at the University of Michigan showed that — contrary to what some experts assume — not all cancer cells are equally capable of producing cancer metastases. In fact, only a tiny fraction (under 1%) can actually cause metastasis. And these highly malignant cells are called stem cells.

Then it was discovered at the University of Massachusetts-Worcester that the cells that initiate malignancy in stomach cancers are not the stomach tissue itself, but the stem cells that migrated from the bone marrow.

This action was initiated by a low-grade stomach infection, usually caused by Helicobacter pylori. In response to this infection, bone-marrow-derived cells (BMDCs) move to the stomach. And once there, these BMDCs take on the characteristics of the surrounding tissue. But they’re influenced by the hormonal signals sent by the inflamed tissue. So they go through a malignant change.

The above-mentioned University of Rochester discoveries about feverfew have been pivotal in giving us a deeper understanding of how stem cells are linked to both cancer genesis and progression.

Dr. Craig Jordan of the University of Rochester said that the reasons some drugs are only moderately effective is “you’re pulling the weed without getting to the root.” Stem cells are the root.

As we’ve said in this newsletter a number of times, stem cells are the most likely reason cancer keeps coming back after a patient appears to be completely well. Very few substances are known to kill them off. One of the few is paw-paw, which we wrote about in Issue 53. If feverfew has the same benefit, it’s very exciting news indeed.

In their laboratories, the University of Rochester team showed that parthenolide is more selective at promoting apoptosis — programmed cell death — than the standard drug cytarabine (Ara-C).

Previous experiments also showed that feverfew compounds can stop cancer cell growth. And a phase I trial also found it was relatively non-toxic.6

Interestingly, a University of Rochester press release claims that someone with leukemia would be unable to consume enough over-the-counter feverfew to stop it from spreading. Ironically, in the absence of clinical trials, it’s not clear how this could have even been established. I also wonder why feverfew has attracted the interest of the NCI when paw-paw’s stem-cell-killing properties have been known for years.

If you’re going to take feverfew…

    The amount of active ingredient parthenolide varies wildly from one plant to another. So you definitely want a standardized product, or you won’t really know what you’re really getting.

Standardized feverfew is available, but you’re well-advised to read labels carefully.

Some products claim to contain 2, 5, or even 7 percent parthenolide by weight. Since some of these supplements apparently come from obscure and unknown companies, do your homework to find products marketed by well-known and reputable companies that have a lot to lose by deceitful marketing or impure products.

One company, Nature’s Way, actually markets three different feverfew products — feverfew leaves, feverfew extract, and a more highly concentrated product called MygraFew which claims it has 2% standardized parthenolide.

A couple of cautions are in order…

    Feverfew is not recommended for pregnant (may cause contractions) or lactating women, nor for children under 2 years of age.

Also, if you’re allergic to ragweed, chamomile, or yarrow, you should not take feverfew. Skin irritation or eczema may occur in those with feverfew allergies.

Further, if you take blood thinning drugs (anticoagulants like warfarin/Coumadin) you should avoid feverfew, as it may increase a risk of bleeding. Of course, readers of this newsletter know that they can get off drug blood-thinners easily, with natural remedies. If feverfew is an effective anticoagulant, why not just reduce the dose of warfarin?

Some people may experience oral discomfort or irritation (swelling of the lips, bleeding of the gums, and loss of taste) when using feverfew.

Other than these side effects, participants in studies have been found to tolerate feverfew well.

If you experience any unusual symptom with feverfew (or anything else, for that matter!) — stop taking the product immediately. Your body chemistry may differ from even people in your own family.

When feverfew intake is suddenly stopped after a long period of use, a patient may experience rebound headaches, anxiety, sleep disturbances, muscle stiffness or pain. You may be able to sidestep this issue by reducing your intake gradually.

Have you tried feverfew for migraines, cancer or other symptoms? Sound off on our Facebook page, and let your health-minded friends in on your experiences.

Our last issue was one of the most interesting we’ve had this year, in my opinion. We wrote about how cutting kids’ tonsils out is not such a good idea, because these little glands pack immune-boosting power that may help avoid cancer and other diseases, too. If you missed this article, you can scroll down and read it now.


Your Hidden, Cancer-Fighting
T-Cell Factory

    As it turns out, tonsils serve an important function in your body.

That runs contrary to long-time medical opinion about the fleshy little bags in the back of your throat. For decades, doctors have been quick to cut them out — often before the patients showed any symptoms of illness.

So thanks to mainstream medical quackery, many adults no longer have their tonsils. But if you’ve still got yours, they might be a valuable cancer-fighter! Keep reading and get the details. . .

Continued below…


Unleashed–Govt health insider tells all

    He couldn’t take it anymore.

One of the country’s most respected M.D.’s witnessed an incident during his tenure with the National Institutes of Health that turned his stomach.

It was the day some of our most powerful researchers turned their backs on clinical evidence for a political agenda. They ignored the science!

It wasn’t the first time–but it was certainly the last time this brave M.D. would stand for it.

What did they change? Why did they change it? And most importantly–how does it affect you?

It does–and the ultimate government insider wants to reveal all in this shocking tell-all video.

Don’t wait another moment. This unbelievable video will NOT be available for long, so don’t delay. This is just the tip of the iceberg…

Watch it here now.


Tonsils are the opposite of useless, according to a team of researchers at the Ohio State University Comprehensive Cancer Center.

It boils down to this: Your tonsils are actually tiny T cell production factories. T cells, if you don’t know, are critical to our immune systems. They’re a type of white blood cell known as lymphocytes that help your body fight infections and other dangerous invaders.

And that includes serious diseases like cancer.

This exciting new research was led by Dr. Michael Caligiuri, director of the OSU cancer center and CEO of the James Cancer Hospital. His team published their riveting findings in a recent issue of the Journal of Clinical Investigation.

5 different levels of disease-fighting tools

    Caligiuri and his team were clued in from some earlier work that showed there was a mystery cell inside the tonsils. So they investigated. But they didn’t just find a few T cells. The Ohio State study actually uncovered T cells in five different stages of development — and all within the tonsils.

Until now, you could set off a fight by suggesting T cells develop anywhere outside of the thymus gland. Researchers used to think T cells only grow in this gland that sits on your heart and is a key part of your immune system. But now it looks like the thymus may not be the only source. The T cells that grow in tonsils aren’t exactly like the ones that form in the thymus, but they’re pretty close.

The research was carried out thanks to donations of tonsil tissue from children who underwent tonsillectomies. T cells in each of the five identified stages were then transferred to lab cultures. From there, the first four groups grew into immune cells, known as natural killer cells. The fifth group developed into mature T cells.

All of those cells have the potential to play a key role in combating major disease.

Most folks no longer have this built-in arsenal

    In the 1950s and 1960s, tonsillectomies were so common, a pair of tonsils were sliced out of some kid’s throat somewhere in the U.S. every 30 seconds. My older brother and sister both had their tonsils removed, although I didn’t. The old 1950 best-seller Cheaper by the Dozen depicted the kids having their tonsils cut out on the dining room table, if I remember right. It wasn’t fiction — it was the true story of the Gilbreth family.

And to think, people ask me why I consider conventional, mainstream medicine to be the real source of most quack medicine.

This moronic medical fad translated to well over a million surgeries a year. And let’s be honest — that also amounted to a lot of revenue for hospitals. At least when the doctors weren’t doing it on the kitchen table (admittedly, the Cheaper by the Dozen events took place in the 1920s).

The rate of tonsillectomies today is down by roughly half of what it was. Hopefully that’s because docs are putting more thought into what they should be slicing and dicing on their patients. Many doctors now prefer to leave tonsils in as long as possible.

Everybody has (or had) two tonsils, made up of soft, glandular tissue. They sit on either side of your mouth, at the back, and vary in size from one person to the next. We’ve long known the major function of tonsils is to trap virus-causing germs and bacteria that you inhale when you breathe. By killing these germs, the tonsils help prevent lung and throat infections. And now we’ve learned they play an even more important role…

What this means …

    Scientists have yet to figure out what actually happens to the T cells that develop in the tonsils. It’s possible they go on to mature in another part of the body. So the next step in this research, according to Caligiuri, is to figure out how many of your mature T cells come from your tonsils rather than your thymus.

The researchers involved with this study are also unsure whether tonsils regularly produce T cells or just start working when your thymus stops. They need to figure out whether T cells from the tonsils serve an upfront purpose, or exist simply as back up to the thymus.

Yet … if you’re battling cancer, or any autoimmune disease, for that matter, wouldn’t you want all the T cells you could get? Doctors say tonsillectomies will continue, especially for patients whose tonsils get so enlarged that it affects their breathing and sleeping. Plus, tonsils can get chronically infected to the point where all they do is fight their own infection. In those cases, tonsillectomies supposedly improve a person’s quality of life.

I wonder if there’s a better way — such as sound nutrition and supplements — that would do a better job than surgery of healing these chronic infections. It reminds me of the chronic ear problems that affect so many children — easily curable by sound alternative medicine, but usually treated by conventional doctors with round after round of antibiotics. Quack! quack!

The new discoveries about tonsils give us profound insight into the bungling of our current health system. Just knowing that millions of adults — and cancer sufferers — had their own personal disease-fighting, immune cell factories cut out, is enough to make me livid.

That’s especially the case since we already know using T cells against cancer-causing viruses is an extremely potent weapon in defeating cancer — especially leukemia. I wrote about it last year in Issue #140.

It’s nice to know you have a back-up natural killer cell and T cell factory in case your thymus ever slows down or stops working. If you still have your tonsils, that is. And if that’s the case, I highly recommend you leave them in.

 

Kindest regards,

Lee Euler Publisher


Footnotes from 1st article:1Martin K, Sur R, Liebel F, et al. Parthenolide-depleted Feverfew (Tanacetum parthenium) protects skin from UV irradiation and external aggression. Arch Dermatol Res. Feb 2008;300(2):69-80.
2Williams CA, Hoult JR, Harborne JB, Greenham J, Eagles J. A biologically active lipophilic flavonol from Tanacetum parthenium. Phytochemistry. Jan. 1995;38(1): 267-270.
3http://preventcancer.aicr.org/site/News2?page+NewsArticle&id=8751&news_iv_ctrl=0&abbr=res
4http://preventcancer.aicr.org/site/News2?page=NewsArticle&id=8751&news_iv_ctrl=0&abbr=res
5Sweeney CJ et al. The sesquiterpene lactone parthenolide in combination with docetaxel reduces metastasis and improves survival in a xenograft model of breast cancer. Molecular Cancer Therapeutics. 2005;4(6):1004-12.
6http://chetday.com/feverfewcancer.htm

References from 2nd article:

C8 Science Panel, Homepage.
http://www.c8sciencepanel.org/

“Chemical in Food Packaging, Fabric Coatings Linked to Cancer.” Environmental Working Group News Release. April 16, 2012.
http://www.ewg.org/release/chemical-food-packaging-fabric-coatings-linked-cancer

“Common chemical PFOA linked to cancer.” by Dr. Mark Stengler, Health Revelations.
http://healthrevelations.com/2012/06/08/everywhere-chemical-in-cancer-link/

“Harmful Teflon Chemical To Be Eliminated by 2015.” By Juliet Eilperin, The Washington Post.
http://www.washingtonpost.com/wp-dyn/content/article/2006/01/25/AR2006012502041.html

“Link between food packaging and cancer.” By Aneka Chohan, The Lahore Times. May 17, 2012.
http://www.lhrtimes.com/2012/05/17/link-between-food-packaging-and-cancer/

Perfluorooctanoic acid. Wikipedia.
http://en.wikipedia.org/wiki/Perfluorooctanoic_acid

“‘Probable link’ between packaging coating and cancer, say scientists.” By Joe Whitworth, FoodProductionDail.com.
http://www.foodproductiondaily.com/Quality-Safety/Probable-link-between-packaging-coating
-and-cancer-say-scientists

“Probably Link Evaluation of Cancer.” C8 Probable Link Report.
http://www.c8sciencepanel.org/pdfs/Probable_Link_C8_Cancer_16April2012.pdf

Shankar, Anoop; Jie Xiao and Alan Ducatman (2011 Oct 15). “Perfluoroalkyl Chemicals and Chronic Kidney Disease in US Adults“.

American Journal of Epidemiology 174 (8): 893-900. doi:10.1093/aje/kwr171. PMID 2187360. Retrieved 2012-6-10.

“Teflon and Perfluorooctanoic Acid (PFOA).” American Cancer Society.
http://www.cancer.org/Cancer/CancerCauses/OtherCarcinogens/AtHome/teflon-and-perfluorooctanoic-acid–pfoa


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Editor in Chief: Lee Euler Contributing Editors: Mindy Tyson McHorse, Carol Parks, Roz Roscoe Marketing: Ric McConnell Information Technology Advisor: Michelle Mato Webmaster: Holly Cornish Fulfillment & Customer Service: Joe Ackerson and Cami Lemr


Health Disclaimer: The information provided above is not intended as personal medical advice or instructions. You should not take any action affecting your health without consulting a qualified health professional. The authors and publishers of the information above are not doctors or health-caregivers. The authors and publishers believe the information to be accurate but its accuracy cannot be guaranteed. There is some risk associated with ANY cancer treatment, and the reader should not act on the information above unless he or she is willing to assume the full risk.

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